Duplication and deletion of the PMP22 gene is associated with Charcot-Marie-Tooth disease (CMT) and Hereditary Neuropathy with Pressure Palsies (HNPP) 15, 16, and several studies have shown that PMP22 regulates tumor development, metastasis, and invasion in different cancers in addition to its functions in neurodevelopmental and neurological disorders17-28, 30. This evidence concerns the gene PMP22 and hereditary neuropathy with liability to pressure palsies.