The outcomes of us found that 12 out of 21 TIICs (dendritic cells resting, B cells naive, macrophages M2, macrophages M0, monocytes, mast cells resting, T cells CD4 memory activated, T cells regulatory (Tregs), plasma cells, T cells CD8, T cells CD4 memory resting, and T cells follicular helper) were all significantly linked to high-risk and low-risk groups, indicating that immune infiltration was significantly related to our established model for ccRCC patients. The gene discussed is CD4; the disease is nonpapillary renal cell carcinoma.