The protein levels of AKR1B10 distinctly correlated with lymph node metastasis (p = 0.016), tumor size (p = 0.010), Ki67 expression (p = 0.036), and p53 expression (p = 2.73E−04) (Table 1). This evidence concerns the gene AKR1B10 and metastatic malignant neoplasm in the lymph nodes.