The result of SROC indicated a moderate ability of LPCAT1 in differentiating between HCC and non-HCC (AUC = 0.80 [0.77, 0.84]; sensitivity = 0.59 [0.42, 0.74]; specificity = 0.85 [0.74, 0.92]; combined diagnostic likelihood ratio positive = 3.98 [2.32, 6.82]; and combined diagnostic likelihood ratio negative = 0.48 [0.34, 0.69]) (Additional file 5: Figure S3a–c). The gene discussed is LPCAT1; the disease is hepatocellular carcinoma.