Newly diagnosed PC after TPL has become an important issue of TPL because of the prolonged lifespan by the resolution of the end-staged organ, introduction of prostate-specific antigen (PSA) screening for early detection of PC, and concerns about the possibility of aggressive PC behavior with rapid cancer progression and poor survival prognoses in the setting of immunosuppression [6, 8–10]. Here, KLK3 is linked to pachyonychia congenita.