Following the rationale of our hypothesis for possible connection between ASLD and PD, we analyzed a recent GWAS dataset of PD (41) and found that ASL is situated 0.5 Mb upstream the risk locus rs76949143 associated with PD, alluding to the potential association between genomic variants in ASL and PD (Fig. 4E). The gene discussed is ASL; the disease is Parkinson disease.