Further, another tumor sample (#648) with a very low percentage of Myc gain (Fig. 5b) engrafted only in two out of four transplanted mice (Table S2), and in the engrafted tumors (#648 T1.1 and #648 T1.2), trisomy of Myc, however, was detected in all CLL cells (Fig. 5b; Table S8). This evidence concerns the gene MYC and B-cell chronic lymphocytic leukemia.