LEP and type 2 diabetes mellitus: Interestingly, we observed that P-MSCs injection to WNIN/GR-Ob (Ob-T2D) rats had restored the expression of both the pro-and anti-inflammatory cytokines, as well as Leptin expression, to the extent seen in the WNIN/Control rats (Figs. 2f,g, 3a,b; Supplementary Fig. 2a–c).