GO analysis showed that 56 genes were enriched in “neuron to neuron synapse”, “postsynaptic density/specialization”, “neuron projection development”, “structural constituent of synapse/postsynapse”, including Akap7, Camk2b, Dlgap1, Tanc1, Tubb2b, Wnt5a, and Zeb2, most of which were downregulated (logFC <0) in the hippocampus of both F1-GDM and F2-GDM. The gene discussed is AKAP7; the disease is gestational diabetes.