CD3E and cancer: After graph-based clustering, 8 cell types were identified based on marker gene expression (Supplementary Fig. 2b, Supplementary Table 3), including cancer cells (n = 73,174) by Wnt10a, NK&T cells (n = 5374) by Cd3e, macrophages (n = 11,823) by C1qc, while classical (n = 11823) and plasmacytoid dendritic cells (n = 352) (cDCs and pDCs) were identified based on H2-Aa and Klk1b27, respectively (Supplementary Fig. 2b, Supplementary Table 3).