ITGB4 and colorectal carcinoma: Combining ITGB4 (1.6 ng/mL) with CEA in the diagnosis of CRC had high specificity (82.0%; 294 false‐positive cases and 1337 true‐negative cases) and an improved sensitivity of 71.4% (70 true‐positive cases, 28 false‐negative cases, Table 1).