CEACAM5 and colorectal carcinoma: The AUC of CEA was 0.632 (95% confidence interval: 0.546–0.718; p = 0.003), and CEA could discriminate CRC patients from HCs with a sensitivity of 16.3% and specificity of 93.2% at a cutoff value of 5 ng/ml (Figure 1B,C).