The best cutoff value of 1.6 ng/mL of ITGB4 could discriminate CRC patients from non‐CRC participants with a sensitivity of 52.0% (51 true‐positive cases and 47 false‐negative cases) and specificity of 86.2% (225 false‐positive cases and 1406 true‐negative cases) in part II (Table 1). The gene discussed is ITGB4; the disease is colorectal carcinoma.