CD4 and asthma: Additional evidence from equine model of severe asthma showed differential expression of several miRNAs (eca-miR-128, eca-miR-744, eca-miR-197, eca-miR-103, eca-miR-107a, eca-miR-30d, eca-miR-140-3p, eca-miR-7, eca-miR-361-3p, eca-miR-148b-3p and eca-miR-215) in serum that regulates airway remodeling and CD4+ T cell maturation and differentiation[28].