STUB1 and Venous thrombosis: As CHIP may induce inflammation of vascular endothelium, as recently well documented inTET2,19it could explain how vascular inflammation leads to clinical PE and also be a missing link between arterial and venous thrombosis, suspected but not yet explored.20As CHIP seems to be involved in many pathological conditions, previously considered as idiopathic, our results open a large amount of future clinical research.