KEGG pathway enrichment analysis results demonstrated that the main signaling pathways regulated by the compound Xuanju capsule were the IL-17 signaling pathway, the TNF signaling pathway, the Th17 cell differentiation pathway, the Toll receptor signaling pathway, the RA pathway, the liquid shear stress and atherosclerosis pathways, etc. It had shown that the TNF signaling pathway was the key pathway derived from the enrichment analysis and an important pathway in the inflammatory response [47]. Here, TNF is linked to rheumatoid arthritis.