KATNAL1 and infertility disorder: In Sertoli cells (SCs), testicular nurse cells that aid in spermatogenic development, KATNAL1 regulates microtubule dynamics involved in spermatid adhesion and release, and KATNAL1 LOF leads to male-specific sterility (Figure 5B; Smith et al., 2012; Hatakeyama and Hayashi, 2018).