The ratio was highest in 6 (85.7%) of the 7 patients with genetic seizures (6 are KCNQ2 seizures, 1 is GABRB3); 15 (36.6%) of the 41 cases of HIE; 3 (30%) of the 10 cases with congenital structural brain malformations; 4 (57.1%) of the 7 hypocalcemic or hypoglycemic seizures (Table 1). Here, GABRB3 is linked to cerebral malformation.