When analyzing the relation of cytokines and liver damage, a trend to higher values in those cases with more severe hepatitis was observed, but it turned out to be significant only for IL-1β (p = 0.026), IL-23 (p = 0.031), IL-8 (p = 0.002), and TGF-β (p = 0.037); while concerning fibrosis severity only IL-8 was associated with advanced fibrosis (p = 0.009) (Figure 4B). The gene discussed is IL1B; the disease is hepatitis A virus infection.