For example, DCs produce IL-12 that activates NK cells to induce the production of IFN-γ, which primes macrophages and neutrophils to enhance phagocytosis and promotes Th1 and effector T cell responses connecting innate to adaptive immune responses against the malaria parasite (Walsh and Mills, 2013; King and Lamb, 2015). The gene discussed is IFNG; the disease is malaria.