Interestingly, GSEA analysis of positively associated genes was enriched in multiple cancer-related pathways, including (1) cell adhesion molecules, (2) chemokine signaling pathway, (3) PI3K-Akt signaling pathways, (4) MAPK signaling pathway, (5) pathways in cancer (Figures 4A, B). The gene discussed is AKT1; the disease is cancer.