In addition, the level of caspase 3 in the tumor tissue was not different among the three groups (control, CDDP, and CDDP plus aspirin); however, the level of cleaved caspase 3 was higher in the CDDP group than in the control group and was higher in the CDDP plus aspirin group than in the CDDP group (Fig. 3E). The gene discussed is CASP3; the disease is neoplasm.