In addition, aspirin induces concentration-dependent inhibition of the major oncogenic pathway, the Wnt/ β-catenin pathway, in colon cancer (Bos et al., 2006) and acetylates the tumor suppressor protein p53 at lysine 382 in MDA-MB-231 breast cancer cells (Alfonso et al., 2009). Here, TP53 is linked to malignant colon neoplasm.