KEGG pathway analysis revealed that the most significantly overrepresented pathways among upmethylated transcripts were the “AMPK signaling pathway,” “longevity regulation pathway,” and “insulin signaling pathway” (Figure 4(e), P < 0.05), while the downmethylated mRNAs were significantly enriched in “glycerophospholipid metabolism,” “ECM-receptor interaction,” and “microRNAs in cancer” (Figure 4(f), P < 0.05). This evidence concerns the gene INS and cancer.