The Kyoto Encyclopedia of Genes and Genome (KEGG) pathway enrichment analysis revealed the altered proteins with their important signal pathway, including renin-angiotensin system, glycosaminoglycan biosynthesis pathway, PPAR signaling pathway, alcoholism, and systemic lupus erythematosu (Figures 1(c) and 1(d)). The gene discussed is PPARA; the disease is alcohol dependence.