TRPV6 and breast carcinoma: We also analyzed the expression of TRPV6 in ER− breast cancer patients and found that the high TRPV6 level is associated with poor overall survival (HR = 1.92, 1.25–3.04; p = 0.0042) and relapse-free survival (HR = 1.31, 1.04–1.64; p = 0.019) (Fig. 7a, b).