For example, some studies reported a higher immunoreactivity and higher levels of a pro-inflammatory cytokine such as IL-6 and anti-inflammatory cytokine such as IL-10 in ADHD children [16, 17], while others found no differences in IL-1b, IL-6, IL-10 levels between ADHD and normal control adults [18, 19]. This evidence concerns the gene IL1B and attention deficit-hyperactivity disorder.