Oncomine analysis also suggested that the transcriptional levels of ceruloplasmin were obviously downregulated in multiple BRCA types, including invasive breast carcinoma, fibroadenoma, invasive ductal breast carcinoma, mixed lobular and ductal breast carcinoma, invasive lobular breast carcinoma and ductal breast carcinoma in situ with respect to normal breast tissues (Figure 1B, 1C and Supplementary Figure 1A). This evidence concerns the gene CP and breast ductal adenocarcinoma.