We found that in luminal B breast cancer, higher expression level of ACE2 was corelated with better prognosis (RFS: HR 0.76, 95%CI=0.63-0.92, p=0.005; DMFS: HR 0.70, 95%CI=0.49-1.00, p=0.046). The gene discussed is ACE2; the disease is breast carcinoma.