EPCAM and neoplasm: According to the biological and physical characteristics of CTCs, the peripheral blood mononuclear cells (PBMCs) of tumor patients were isolated and passed through a microfluidic chip coated with EpCAM antibody under stable and slow laminar flow control, and EpCAM + cells were captured by EpCAM antibody and bound to the bottom of the chip, while the remaining lymphocytes flowed out with the liquid, as in the CTCs-i Chip method [32, 33].