In addition, the multivariate logistic regression analysis demonstrated that hs-CRP (OR, 1.103; 95% CI: 1.005–1.210; P = 0.040), LAD (OR, 1.096; 95% CI, 1.042–1.153; P < 0.001), and plasma CA-125 (OR, 1.121; 95% CI: 1.075–1.169; P < 0.001) were independent risk factors of AF recurrence following RFCA (Table 6). The gene discussed is CRP; the disease is atrial fibrillation.