The specific markers that we analyzed include tumor stem cell markers (CD24, CD44), markers of immunosuppression (CD47, PD-L1), markers of cell adhesion (CD49d, ICAM-1), markers of lymphocytes co-stimulation (CD80, CD86), and markers of antigen presentation (MHC class I, MHC class II). This evidence concerns the gene ITGA4 and neoplasm.