As shown in Figure 4B, 4C, the mRNA levels of M1 macrophage markers CD68, IL-6, and IL-1β were higher in the BPH group than in the Con group, while the mRNA levels of M2 macrophage markers CD206, ARG1, and IL-10 were lower in the BPH group. The gene discussed is IL1B; the disease is benign prostatic hyperplasia.