PRKN and endometriosis: PRCC-TFE3 tRCC is a TFE3 Xp11.2 translocation renal cell carcinoma (TFE3-tRCC) that promotes cell survival and proliferation by implicating in PINK1-PRKN/parkin-dependent mitophagy and activating the expression of the E3 ubiquitin ligase PRKN, leading to rapid PINK1-PRKN-dependent mitophagy that promotes cell survival under mitochondrial oxidative damage as well as cell proliferation by decreasing mitochondrial ROS formation [68], suggesting that there are similar regulatory mechanisms in endometriosis.