Furthermore, across all CRC organoids, we observed a positive correlation between p‐ERK and KI67 protein levels (P < 0.005) and a negative correlation between p‐ERK and cleaved Caspase3 (P < 0.005) and cleaved PARP levels, in line with roles of MAPK in activation of proliferation and inhibition of apoptosis. Here, PARP1 is linked to colorectal carcinoma.