Raetz's group [Gibbons et al., 2000] proposed another interesting hypothesis that could explain the role of 2OH-C14 as a virulence factor: during infection, 2-hydroxymyristic acids released by LPS through leukocyte acyloxyacyl hydrolase would be converted to 2-hydroxymyristoyl coenzyme A, a well-known potent inhibitor of N-myristoyl transferase that is required for cell signaling. Here, AOAH is linked to infection.