ELK3 and familial pancreatic carcinoma: As shown in Table 1 and Supplementary Figure 5D, ELK3 expression was significantly higher in pancreatic cancer tissues of T3 stage, N1stage, distant metastasis M1 stage and AJCC stage IIB-IV than in these of T1–T2 stage, N0 stage, M1 stage and AJCC-IIA stage, respectively (P < 0.05 for all).