BCAN and central nervous system cancer: Brain-enriched hyaluronan-binding protein (BEHAB) is an N-terminally cleaved (Matthews et al., 2000) bioactive fragment of brevican that is dramatically increased in human gliomas (Nutt et al., 2001; Viapiano et al., 2008) where it promotes glial cell motility and the aggressiveness of gliomas (Yamaguchi, 1996; Gary and Hockfield, 2000; Nutt et al., 2001; Viapiano et al., 2008; Giamanco and Matthews, 2020).