After establishing the association of CLEC4s expression with HCC outcome via the GEPIA database, we found that patients expressing higher CLEC4H1 (ASGR1, P = 0.013) and CLEC4H2 (ASGR2, P = 0.018) levels were characterized by longer overall survival compared to patients exhibiting lower expression (Supplementary Figures 4A–K). Here, ASGR2 is linked to hepatocellular carcinoma.