The results showed that tumor volumes were decreased in the RORA-OE group, the CASC2-KD1+RORA-OE group, and the EIF4A3-OE+RORA-OE group when compared with the control group, while the tumor volumes were significantly increased in the CASC2-KD1 group and the EIF4A3-OE group compared with the control group (Figures 7A, B). This evidence concerns the gene CASC2 and neoplasm.