Interestingly, many of the genes expressed in a MAPK10-associated manner were chemokines and cytokines (Figures 4A, B and Table S3), demonstrating that HCC patients with high MAPK10 expression had increased chemokine and cytokine expression in the TME compared to patients with low MAPK10 expression. The gene discussed is MAPK10; the disease is hepatocellular carcinoma.