In combination with our in silico finding that HCC patients with high MAPK10 expression had significantly higher expression scores of stromal cells (Figures 2A, B) and infiltrating immune cells (Figures 2C, D) but lower scores of tumor cells (Figures 2E, F) in their tumor microenvironment compared to patients with low MAPK10 expression, we propose that high expression of MAPK10 in liver cancer tissues might promote the infiltration of immunocytes and the secretion of chemokine and cytokines. This evidence concerns the gene MAPK10 and neoplasm.