To analyze the prognostic significance of MAPK10 expression, pan-cancer analysis using TCGA data was conducted utilizing the web interface of the Tumor IMmune Estimation Resource 2.0 (TIMER 2.0, http://timer.comp-genomics.org/).The pan-cancer analysis showed that MAPK10 was extensively down-regulated in a wide variety of solid tumor tissue (Figure 1A). The gene discussed is MAPK10; the disease is cancer.