MAPK10 and liver cancer: We found, by using qPCR, that the expression of ICAM1 in MAPK10-overexpressing HepG2-MAPK10 cell line was significantly higher than in the control HepG2-puro cell line, suggesting that MAPK10 is able to promote the expression of the co-stimulatory molecule ICAM1 in liver cancer cells (P < 0.0001; Figure 6C).