IFNA1 and hepatocellular carcinoma: The third group of HCC patients (Cluster 2 in Supplementary Figure 1C, n = 108) who had medium content of distinct immune cells, medium expression of major histocompatibility complex class I/II (MHC-I/II), medium expression of the genes involved in the IFN response, inflammation and cytolytic activity were classified as HCC patients with medium immune activity.