The results showed that CKS1B overexpression significantly decreased the expression of Cleaved Caspase-3 and Cleaved PARP, while knockdown of CKS1B significantly increased the expression of Cleaved Caspase-3 and Cleaved PARP in HCC cells (Figure 2(B)). The gene discussed is CKS1B; the disease is hepatocellular carcinoma.