This meta-analysis demonstrated that, compared with Western medicine alone, the combination of QQC and Western medicine exerted more positive effects on improving efficacy and increasing the level of LVEF, LVEDD, and 6MWT, as well as reducs the adverse effects and the level of HR, LVESD, BNP, Hs-cTnT of patients with CHF. Here, NPPB is linked to congestive heart failure.