MYC and cancer: In conclusion, we show that environmental relevant dose of ionizing radiation can alter the expression of gene cluster related to DNA damage response through the control of MYC, which agreed with other studies reporting amplification of MYC gene in somatic cells and cancer cells (Sawey et al., 1987; Mothersill et al., 1991; Käcker et al., 2013; Ginter et al., 2014).