Particularly, we found PDPK1 and TAB2 associated with HF which have been well documented for playing a crucial role in heart complications (Kuzmanov et al., 2016; Yin et al., 2017; Marrocco et al., 2019; Chen et al., 2020; Cheng et al., 2020). The gene discussed is PDPK1; the disease is hydrops fetalis.