TXNRD2 and open-angle glaucoma: With several polymorphisms reported to be associated with POAG or related endophenotypic traits (Abu-Amero et al., 2015), we investigated whether SNPs rs35934224 (TXNRD2) and rs6478746 (LMX1B) are associated with POAG in the middle-eastern cohort of Saudi Arabia and report a negative association of these variants with POAG in this ethnic group.