These include the rs35934224 in the thioredoxin reductase 2 (TXNRD2) genomic region (Bailey et al., 2016), and rs6478746 on chromosome 9 near LIM homeobox transcription factor 1 beta (LMX1B) and an uncharacterized RNA gene, LOC105376277 identified among the POAG patients of European ancestry (Gharahkhani et al., 2018). Here, TXNRD2 is linked to open-angle glaucoma.