Although rs6478746 has not been evaluated in other ethnic groups, different variants in LMX1B, such as rs55770306 was associated with POAG in the Genetic Epidemiology Research in Adult Health and Aging (GERA) cohort (p = 0.00019) consisting of the non-Hispanic whites, Hispanic/Latinos, East Asians, and African-Americans, and the UK Biobank (UKB) cohort (p = 5.5 × 10−14) in the same study (Choquet et al., 2018); and rs10819187 was identified in a Japanese GWAS (p = 4.4 × 10−12) (Shiga et al., 2018) supporting the role of LMX1B in POAG. Here, LMX1B is linked to open-angle glaucoma.