EGFR and diabetes mellitus: It is noteworthy that, despite its inhibitory effects on EGFR and other ErbB receptors (Akhtar et al., 2012b; Akhtar et al., 2015), Ang-(1–7) exerts considerable cardioprotective effects in models of diabetes (Dhaunsi et al., 2010; Yousif et al., 2012; Benter et al., 2014; Abwainy et al., 2016).