CX3CL1 and neurodegenerative disease: Based on the number of studies indicated above on the therapeutic viability of using AAV or peptides to overexpress soluble FKN for the treatment of neurodegenerative diseases, it will be of great interest to examine the effects of overexpression of FKN as a viable treatment option for the survival of SGNs and regeneration of damaged ribbon synapses following cochlear trauma.