Meanwhile, Wang et al. found that LINC00941 could act as a competing endogenous RNA (ceRNA) by sponging miR-335-5p to regulate ROCK1-mediated LIMK1/Cofilin-1 signaling, which contributed to the proliferation, migration, invasion, and EMT of pancreatic cancer cells52. Here, CFL1 is linked to familial pancreatic carcinoma.