Vaccinated and unvaccinated nursing home staff were also similar in terms of sex, but differed in age, prevalence of some comorbidities (obesity, hypertension, osteoarthritis), and medicine use (lipid modifying drugs and angiotensin converting enzyme inhibitors/angiotensin receptor blockers), all with standardised mean difference >0.1. This evidence concerns the gene ACE and obesity due to melanocortin 4 receptor deficiency.