Similarly, Zhang et al. [19] confirmed the low expression of miR-150-5p in osteoarthritis, which negatively impacted the AKT serine/threonine kinase 3 (AKT3) pathway to promote chondrocyte proliferation and inhibit apoptosis and degradation of extracellular matrix in chondrocytes. This evidence concerns the gene AKT3 and osteoarthritis.