Furthermore, HCC cells exposed to ART showed downregulation of pro-metastatic and pro-invasive protein N-cadherin, MMP2, MMP9, and Snail, while the expression of anti-metastatic protein E-cadherin was upregulated, suggesting that ART may suppress the migration and invasion of HCC cells by adjusting the N-cadherin-snail-E-cadherin axis [60]. Here, CDH2 is linked to hepatocellular carcinoma.