After dividing the colon cancer patients into two groups based on the frequency of CD39+ Treg among intratumoral Treg, we could also show that CD39+ Treg in the tumors have higher Foxp3 expression on a per cell basis if they are isolated from tumors with a high infiltration of CD39+ Treg compared to tumors with fewer CD39+ Treg. This evidence concerns the gene ENTPD1 and colonic neoplasm.