To investigate if MSS/MSI-status in colon cancer could contribute to the presence of CD39+ intratumoral Treg, we stratified our sample for group I and II, but there was no significant difference between MSI-H and MSS tumors regarding the frequency of intratumoral CD39+ Treg (Fig. 3B). Here, ENTPD1 is linked to malignant colon neoplasm.